Theoretical study on the design of allosteric inhibitors of diabetes associated protein PTP1B
The protein tyrosine phosphatase 1B (PTP1B) is a critical therapeutic target for type 2 diabetes mellitus (T2DM). Many PTP1B inhibitors have been reported, however, most of them lack high specificity and have adverse effects. Designing effective PTP1B inhibitors requires understanding the molecular...
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| Format: | Book |
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Frontiers Media S.A.,
2024-08-01T00:00:00Z.
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