Prognosis of childhood abdominopelvic rhabdomyosarcoma: Case series

• Main Authors: Kokoé Agblévi Midékor Gonébo (Author), Moufidath Sounkéré Soro (Author), Rébécca Bonny Obro (Author), Amenan Kan Sophie Kouassi Dria (Author), Sigué Jean Jaurès Ouattara (Author), Yapi Landry Aké (Author), Nicolas Moh Ello (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Introduction: Rhabdomyosarcoma, the most common malignant mesenchymal tumour in children, primarily affects the urogenitals. In Europe, the prognosis of the localised forms is excellent, whereas in sub-saharan Africa, it is reserved. This observation study aimed to report the diagnostic, therapeutic, evolutionary, and prognostic aspects of rhabdomyosarcoma. Case presentation: This was a series of six observations in four boys and two girls, all of whom had no significant medical history. An abdominal mass in two patients and a pelvic mass in the others evolved over 10 days to 4 months. All localizations were complicated by signs of compression: urinary for the pelvic and digestive for the abdomen. CT tomography revealed urogenital localisation in four patients and abdominal localisation in one patient. A histological examination revealed embryonic rhabdomyosarcoma in all patients. Chemotherapy was neoadjuvant in five patients and postoperative in one patient. Immediate tumour resection was performed in one patient. All patients died: five during chemotherapy and one following recurrence after 1 year of remission. Conclusion: The prognosis of rhabdomyosarcomas is linked to delays in consultation, tumour size, histological type, and therapeutic difficulties. Adequate management of this condition requires multidisciplinary consultation.

Item Description

2213-5766
10.1016/j.epsc.2023.102633