A combined molecular typing approach does not discriminate Legionella pneumophila serogroup 1 strains of a predominant sequence-based type in Palermo, Italy

Summary: The sequence-based type 1,4,3,1,1,1 of Legionella pneumophila sg.1 is predominant in the Palermo city environment since several years. In this study, extended sequence-based typing and pulsed field gel electrophoresis were used in a combined approach in the aim to enhance discriminatory pow...

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Main Authors: Celestino Bonura (Author), Caterina Mammina (Author), Antonietta Vella (Author), Santina Belfiore (Author), Alfredo Chiarini (Author), Anna Giammanco (Author)
Format: Book
Published: Elsevier, 2009-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Celestino Bonura  |e author 
700 1 0 |a Caterina Mammina  |e author 
700 1 0 |a Antonietta Vella  |e author 
700 1 0 |a Santina Belfiore  |e author 
700 1 0 |a Alfredo Chiarini  |e author 
700 1 0 |a Anna Giammanco  |e author 
245 0 0 |a A combined molecular typing approach does not discriminate Legionella pneumophila serogroup 1 strains of a predominant sequence-based type in Palermo, Italy 
260 |b Elsevier,   |c 2009-01-01T00:00:00Z. 
500 |a 1876-0341 
500 |a 10.1016/j.jiph.2009.09.003 
520 |a Summary: The sequence-based type 1,4,3,1,1,1 of Legionella pneumophila sg.1 is predominant in the Palermo city environment since several years. In this study, extended sequence-based typing and pulsed field gel electrophoresis were used in a combined approach in the aim to enhance discriminatory power of the molecular typing procedures. However, probably due to a common environmental reservoir and genetic stability, most of the strains circulating in the geographic area under study belong to the same clone and are, consequently, indistinguishable by molecular typing. Investigations of clinical cases and tracing to their environmental source require caution and support from sound epidemiological data. Keywords: Legionella pneumophila, Molecular typing, Epidemiology, SBT, PFGE 
546 |a EN 
690 |a Infectious and parasitic diseases 
690 |a RC109-216 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n Journal of Infection and Public Health, Vol 2, Iss 4, Pp 184-188 (2009) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S1876034109000641 
787 0 |n https://doaj.org/toc/1876-0341 
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