Phosphate Homeostasis, Inflammation and the Regulation of FGF-23

• Κύριοι συγγραφείς: Florian Lang (Συγγραφέας), Christina Leibrock (Συγγραφέας), Aleksandra A. Pandyra (Συγγραφέας), Christos Stournaras (Συγγραφέας), Carsten A. Wagner (Συγγραφέας), Michael Föller (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Karger Publishers, 2018-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Fibroblast growth factor 23 (FGF23) is released primarily from osteoblasts/osteocytes in bone. In cooperation with the transmembrane protein Klotho, FGF23 is a powerful inhibitor of 1α 25OH Vitamin D Hydroxylase (Cyp27b1) and thus of the formation of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). As 1,25(O...