Vulvoperineal Crohn's disease responsive to metronidazole

• Main Authors: Aristóteles Rosmaninho (Author), Madalena Sanches (Author), Marta Salgado (Author), Rosário Alves (Author), Manuela Selores (Author)
• Format: Book
• Published: Sociedade Brasileira de Dermatologia, 2013-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 0365-0596; 10.1590/abd1806-4841.20132243
• Keywords: Crohn disease; Metronidazole; Therapeutics; Dermatology; RL1-803
• Source: Anais Brasileiros de Dermatologia, Vol 88, Iss 6 suppl 1, Pp 71-74 (2013)

Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological lesions are the inaugural event and may constitute the only sign of the disease. Vulvoperineal involvement is rare, may precede bowel symptoms by months to years and may go unrecognized. Due to the paucity of reports of Crohn's disease at this location and in the absence of randomized trials, there are no standard treatments for the cutaneous disease. We describe the case of a 47 year-old woman with vulvoperineal Crohn's disease without digestive involvement, that was successfully managed with metronidazole.