Effect of maternal praziquantel treatment for Schistosoma japonicum infection on the offspring susceptibility and immunologic response to infection at age six, a cohort study.

• Main Authors: Susannah Colt (Author), Blanca Jarilla (Author), Palmera Baltazar (Author), Veronica Tallo (Author), Luz P Acosta (Author), Hannah W Wu (Author), Christopher V Barry (Author), Jonathan D Kurtis (Author), Remigio M Olveda (Author), Jennifer F Friedman (Author), Mario A Jiz (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In areas endemic to schistosomiasis, fetal exposure to schistosome antigens prime the offspring before potential natural infection. Praziquantel (PZQ) treatment for Schistosoma japonicum infection in pregnant women has been demonstrated to be safe and effective. Our objectives were to evaluate wheth...