A rare case of angiomyomatous hamartoma of periaortic lymph node and synchronous angiomyolipoma of the kidney: a diagnostic pitfall for lymph node involvement by angiomyolipoma

Angiomyomatous hamartoma is a rare benign proliferative lesion of lymph nodes, showing replacement of the lymph node parenchyma by irregular thick-walled blood vessels, smooth muscle, fibrotic stroma and variable amount of adipose tissue. These histologic features greatly overlap with those describe...

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Bibliographic Details
Main Authors: Zsolt Jobbagy (Author), Claudio Guerrieri (Author), Domenico Savatta (Author), Sairam Chattu (Author), Billie Fyfe-Kirschner (Author)
Format: Book
Published: Elsevier, 2020-03-01T00:00:00Z.
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Summary:Angiomyomatous hamartoma is a rare benign proliferative lesion of lymph nodes, showing replacement of the lymph node parenchyma by irregular thick-walled blood vessels, smooth muscle, fibrotic stroma and variable amount of adipose tissue. These histologic features greatly overlap with those described in angiomyolipoma, a member of the perivascular epithelioid cell tumor (PEComa) family. We present a unique case of angiomyomatous hamartoma of a periaortic lymph node, which mimicked lymph node involvement in a patient with renal angiomyolipoma on hematoxylin and eosin (H&E) stained slides alone. Keywords: Renal angiomyolipoma, Angiomyomatous hamartoma, Periaortic lymph node, Angiomyolipoma in lymph node, Melanocytic immunomarkers, Cathepsin K
Item Description:2214-3300
10.1016/j.ehpc.2020.200361