Bi-stream CNN Down Syndrome screening model based on genotyping array

• Main Authors: Bing Feng (Author), William Hoskins (Author), Yan Zhang (Author), Zibo Meng (Author), David C. Samuels (Author), Jiandong Wang (Author), Ruofan Xia (Author), Chao Liu (Author), Jijun Tang (Author), Yan Guo (Author)
• Format: Book
• Published: BMC, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Human Down syndrome (DS) is usually caused by genomic micro-duplications and dosage imbalances of human chromosome 21. It is associated with many genomic and phenotype abnormalities. Even though human DS occurs about 1 per 1,000 births worldwide, which is a very high rate, resear...