Understanding the mechanisms of food effect on omaveloxolone pharmacokinetics through physiologically based biopharmaceutics modeling
Abstract Omaveloxolone is a nuclear factor (erythroid‐derived 2)‐like 2 activator approved in the United States and the European Union for the treatment of patients with Friedreich ataxia aged ≥16 years, with a recommended dosage of 150 mg orally once daily on an empty stomach. The effect of the US...
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Main Authors: | Xavier J. H. Pepin (Author), Scott M. Hynes (Author), Hamim Zahir (Author), Deborah Walker (Author), Lois Q. Semmens (Author), Sandra Suarez‐Sharp (Author) |
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Format: | Book |
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Wiley,
2024-10-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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