Species-specific antimonial sensitivity in Leishmania is driven by post-transcriptional regulation of AQP1.

• Main Authors: Goutam Mandal (Author), Srotoswati Mandal (Author), Mansi Sharma (Author), Karen Santos Charret (Author), Barbara Papadopoulou (Author), Hiranmoy Bhattacharjee (Author), Rita Mukhopadhyay (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmania is a digenetic protozoan parasite causing leishmaniasis in humans. The different clinical forms of leishmaniasis are caused by more than twenty species of Leishmania that are transmitted by nearly thirty species of phlebotomine sand flies. Pentavalent antimonials (such as Pentostam or Glu...