Striatal phosphodiesterase 10A availability is altered secondary to chronic changes in dopamine neurotransmission
Abstract Background Phosphodiesterase 10A (PDE10A) is an important regulator of nigrostriatal dopamine (DA) neurotransmission. However, little is known on the effect of alterations in DA neurotransmission on PDE10A availability. Here, we used [18F]JNJ42259152 PET to measure changes in PDE10A availab...
Saved in:
Main Authors: | Maarten Ooms (Author), Sofie Celen (Author), Ronald De Hoogt (Author), Ilse Lenaerts (Author), Johnny Liebregts (Author), Greet Vanhoof (Author), Xavier Langlois (Author), Andrey Postnov (Author), Michel Koole (Author), Alfons Verbruggen (Author), Koen Van Laere (Author), Guy Bormans (Author) |
---|---|
Format: | Book |
Published: |
SpringerOpen,
2016-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Biochemical and Behavioral Profiles of Phosphodiesterase Inhibition in Dopaminergic Neurotransmission
by: Akinori Nishi, et al.
Published: (2010) -
Endocannabinoid-dopamine interactions in striatal synaptic plasticity
by: Brian Neil Mathur, et al.
Published: (2012) -
Dysregulation of dopamine neurotransmission in the nucleus accumbens in immobilization-induced hypersensitivity
by: Yuki Kishikawa, et al.
Published: (2022) -
Striatal But Not Extrastriatal Dopamine Receptors Are Critical to Dopaminergic Motor Stimulation
by: Yuhan Wang, et al.
Published: (2017) -
Mechanisms for the modulation of dopamine D1 receptor signaling in striatal neurons
by: Akinori eNishi, et al.
Published: (2011)