Renal fibrosis

Renal fibrosis, characterized by tubulointerstitial fibrosis and glomerulosclerosis, is the final manifestation of chronic kidney disease. Renal fibrosis is characterized by an excessive accumulation and deposition of extracellular matrix components. This pathologic result usually originates from bo...

Full description

Saved in:
Bibliographic Details
Main Author: Min Hyun Cho (Author)
Format: Book
Published: Korean Pediatric Society, 2010-07-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_d51b69b3c85d434e8855d0391b70845b
042 |a dc 
100 1 0 |a Min Hyun Cho  |e author 
245 0 0 |a Renal fibrosis 
260 |b Korean Pediatric Society,   |c 2010-07-01T00:00:00Z. 
500 |a 1738-1061 
500 |a 2092-7258 
500 |a 10.3345/kjp.2010.53.7.735 
520 |a Renal fibrosis, characterized by tubulointerstitial fibrosis and glomerulosclerosis, is the final manifestation of chronic kidney disease. Renal fibrosis is characterized by an excessive accumulation and deposition of extracellular matrix components. This pathologic result usually originates from both underlying complicated cellular activities such as epithelial-to-mesenchymal transition, fibroblast activation, monocyte/macrophage infiltration, and cellular apoptosis and the activation of signaling molecules such as transforming growth factor beta and angiotensin II. However, because the pathogenesis of renal fibrosis is extremely complicated and our knowledge regarding this condition is still limited, further studies are needed. 
546 |a EN 
690 |a Fibrosis 
690 |a Glomerulosclerosis 
690 |a Kidney disease 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Korean Journal of Pediatrics, Vol 53, Iss 7, Pp 735-740 (2010) 
787 0 |n http://kjp.or.kr/upload/pdf/kjped-53-735.pdf 
787 0 |n https://doaj.org/toc/1738-1061 
787 0 |n https://doaj.org/toc/2092-7258 
856 4 1 |u https://doaj.org/article/d51b69b3c85d434e8855d0391b70845b  |z Connect to this object online.