MLIF Modulates Microglia Polarization in Ischemic Stroke by Targeting eEF1A1

• Main Authors: Yulan Liu (Author), Shanshan Deng (Author), Zhibing Song (Author), Qian Zhang (Author), Yuchen Guo (Author), Yongsheng Yu (Author), Yuliang Wang (Author), Tiejun Li (Author), Fayed A. K. Megahed (Author), Tamer A. Addissouky (Author), Junqin Mao (Author), Yuefan Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Monocyte locomotion inhibitory factor (MLIF) is a heat-stable pentapeptide from Entamoeba histolytica. Our previous study found that MLIF protects against ischemic stroke in rats and mice and exerts a neuroprotection effect in human neuroblastoma SH-SY5Y cells. Microglia/macrophage polarization has...