Molecular docking and statistical optimization of taurocholate-stabilized galactose anchored bilosomes for the enhancement of sofosbuvir absorption and hepatic relative targeting efficiency
The work aimed to improve both absorption and hepatic availability of sofosbuvir. Bilosomes and galactose-anchored bilosomes were investigated as potential nanocarriers for this purpose. Sofosbuvir is a class III drug with high solubility and low permeability. Thus, the drug entrapment into lipid-ba...
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Main Authors: | Marianne Joseph Naguib (Author), Amira Moustafa Kamel (Author), Ahmed Thabet Negmeldin (Author), Ahmed Hassen Elshafeey (Author), Ibrahim Elsayed (Author) |
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Format: | Book |
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Taylor & Francis Group,
2020-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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