Investigation of catalytic oxidation of 4-nitroethylbenzene by ozone to 4-nitroacetophenone - an intermediate in the synthesis of antibiotics
4-Nitroacetophenone is an important intermediate for the manufacture of broad-spectrum antibiotics, in particular chloramphenicol. Existing methods of ketone synthesis are imperfect. The disadvantage of the simplest of them (the oxidation of 4-nitroethylbenzene by oxygen at atmospheric pressure and...
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Zaporozhye State Medical University,
2021-07-01T00:00:00Z.
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