MYOCARDIAL REMODELING IN ISCHEMIC HEART DISEASE

• Glavni autori: A. N. Zakirova (Autor), R. G. Oganov (Autor), N. E. Zakirova (Autor), G. R. Klochkova (Autor), F. S. Musina (Autor)
• Format: Knjiga
• Izdano: Столичная издательская компания, 2016-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Sažetak

<p><strong>Aim.</strong> To study the myocardial remodeling features in patients with stable angina depending on disease severity and experienced myocardial infarction (MI).</p><p><strong>Material and methods.</strong> 148 male patients with stable angina were examined and randomized into 3 groups (G1-G3). 52 patients of G1 had angina of I-II functional class (FC). 49 patients of G2 had angina of III FC, and 47 patients of G3 had angina of IV FC. History of MI had 79,5, 87.2 and 92.6% of patients in G1, G2 and G3 respectively. 35 healthy men were included into control group. Coronarography, bicycle ergometry and 24-hour ECG monitoring was performed. Left ventricular (LV) function and remodeling was assessed with echocardiography.</p><p><strong>Results.</strong> G3 patients had LV eccentric hypertrophy as a result of postinfarction cardiosclerosis which accompanied with LV systolic dysfunction, a myocardial stress increasing and LV spherification. G1 patients had no any significant disorders of LV systolic function.</p><p><strong>Conclusion.</strong> Severe ischemic heart disease is associated with a dysadaptive remodeling unlike mild ischemic heart disease, which is associated with an adaptive myocardial remodeling.</p>

Opis predmeta

1819-6446
2225-3653
10.1234/1819-6446-2009-1-42-45