The Complexity of Bariatric Patient's Pharmacotherapy: Sildenafil Biopharmaceutics and Pharmacokinetics before vs. after Gastric Sleeve/Bypass

Postbariatric altered gastrointestinal (GI) anatomy/physiology may significantly harm oral drug absorption and overall bioavailability. In this work, sildenafil, the first phosphodiesterase-5 (PDE5) inhibitor, was investigated for impaired postbariatric solubility/dissolution and absorption; this re...

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Bibliographic Details
Main Authors: Daniel Porat (Author), Oleg Dukhno (Author), Sandra Cvijić (Author), Arik Dahan (Author)
Format: Book
Published: MDPI AG, 2023-12-01T00:00:00Z.
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