Mysteries of α1-antitrypsin deficiency: emerging therapeutic strategies for a challenging disease
The classical form of α1-antitrypsin deficiency (ATD) is an autosomal co-dominant disorder that affects ~1 in 3000 live births and is an important genetic cause of lung and liver disease. The protein affected, α1-antitrypsin (AT), is predominantly derived from the liver and has the function of inhib...
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Main Authors: | Raafe Ghouse (Author), Andrew Chu (Author), Yan Wang (Author), David H. Perlmutter (Author) |
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Format: | Book |
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The Company of Biologists,
2014-04-01T00:00:00Z.
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