Down-Regulation of Renal Klotho Expression by Shiga Toxin 2
Background/Aims: Shiga toxin 2 may trigger classical hemolytic uremic syndrome (HUS) eventually leading to renal failure. Klotho, a transmembrane protein, protease and hormone mainly expressed in kidney is involved in the regulation of renal phosphate excretion and also retains renal protective effe...
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Karger Publishers,
2014-11-01T00:00:00Z.
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