Down-Regulation of Renal Klotho Expression by Shiga Toxin 2

• Główni autorzy: Martina Feger (Autor), Sobuj Mia (Autor), Tatsiana Pakladok (Autor), Jan P. Nicolay (Autor), Ioana Alesutan (Autor), Stefan W. Schneider (Autor), Jakob Voelkl (Autor), Florian Lang (Autor)
• Format: Książka
• Wydane: Karger Publishers, 2014-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background/Aims: Shiga toxin 2 may trigger classical hemolytic uremic syndrome (HUS) eventually leading to renal failure. Klotho, a transmembrane protein, protease and hormone mainly expressed in kidney is involved in the regulation of renal phosphate excretion and also retains renal protective effe...