<it>PRNP </it>variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism

• Auteurs principaux: Will Robert G (Auteur), Heath Craig A (Auteur), Pennington Catherine (Auteur), Bishop Matthew T (Auteur), Knight Richard SG (Auteur)
• Format: Livre
• Publié: BMC, 2009-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Genetic analysis of the human prion protein gene (<it>PRNP</it>) in suspect cases of Creutzfeldt-Jakob disease (CJD) is necessary for accurate diagnosis and case classification. Previous publications on the genetic variat...