Fatal Epileptic Seizures in Mice Having Compromised Glutathione and Ascorbic Acid Biosynthesis
Reduced glutathione (GSH) and ascorbic acid (AA) are the two most abundant low-molecular-weight antioxidants in mammalian tissues. <i>Gclm<sup>KO</sup></i> knockout mice lack the gene encoding the modifier subunit of the rate-limiting enzyme in GSH biosynthesis; <i>Gclm...
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Main Authors: | Ying Chen (Author), Katherine D. Holland (Author), Howard G. Shertzer (Author), Daniel W. Nebert (Author), Timothy P. Dalton (Author) |
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Format: | Book |
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MDPI AG,
2023-02-01T00:00:00Z.
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