Cartilage targeted chemical delivery of naproxen and ibuprofen for the treatment of arthritis
NSAIDs are among the most widely used prescription drugs, for the treatment of pain and inflammation, particularly arthritis. Inhibitor of COX and NSAIDs relieve the signs and symptoms of inflammation by decreasing PG production but may cause GI and renal damage. Synthesis, stability studies and Y-i...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Wolters Kluwer Medknow Publications,
2012-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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| Summary: | NSAIDs are among the most widely used prescription drugs, for the treatment of pain and inflammation, particularly arthritis. Inhibitor of COX and NSAIDs relieve the signs and symptoms of inflammation by decreasing PG production but may cause GI and renal damage. Synthesis, stability studies and Y-imaging studies are carried out. Cartilage targeting strategy for conventional NSAIDs has been explored for reducing their local and systemic side effect of the NSAIDs site specific delivery of quarternary ester derivatives could have to be an effective strategy for long term therapy of inflammatory conditions like arthritis. |
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| Item Description: | 0975-7406 0976-4879 10.4103/0975-7406.94119 |