Successful treatment of refractory chronic bullous disease of childhood with rituximab
Chronic bullous disease of childhood is a rare subepidermal bullous disease with a hallmark of linear IgA deposition along basement membrane zone seen on direct immunofluorescence. We report a case of a 2-year-old male child, who had recurrent and multiple bullous eruptions over body and he was not...
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Wolters Kluwer Medknow Publications,
2022-01-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_d709b4530d064a37b4eb5ebe428f1a25 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Debdeep Mitra |e author |
| 700 | 1 | 0 | |a Anuj Bhatnagar |e author |
| 700 | 1 | 0 | |a Gautam K Singh |e author |
| 700 | 1 | 0 | |a Sunmeet Sandhu |e author |
| 245 | 0 | 0 | |a Successful treatment of refractory chronic bullous disease of childhood with rituximab |
| 260 | |b Wolters Kluwer Medknow Publications, |c 2022-01-01T00:00:00Z. | ||
| 500 | |a 2229-5178 | ||
| 500 | |a 10.4103/idoj.idoj_223_21 | ||
| 520 | |a Chronic bullous disease of childhood is a rare subepidermal bullous disease with a hallmark of linear IgA deposition along basement membrane zone seen on direct immunofluorescence. We report a case of a 2-year-old male child, who had recurrent and multiple bullous eruptions over body and he was not responding to conventional therapy. He had earlier developed a drug reaction to dapsone which is considered the drug of choice for this condition. We report successful management of this case with injection rituximab which is a chimeric monoclonal antibody against CD20, which is primarily found on the surface of B cells. | ||
| 546 | |a EN | ||
| 690 | |a chronic bullous disease of childhood (cbdc) | ||
| 690 | |a dapsone hypersensitivity | ||
| 690 | |a rituximab | ||
| 690 | |a Dermatology | ||
| 690 | |a RL1-803 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Indian Dermatology Online Journal, Vol 13, Iss 2, Pp 248-251 (2022) | |
| 787 | 0 | |n http://www.idoj.in/article.asp?issn=2229-5178;year=2022;volume=13;issue=2;spage=248;epage=251;aulast=Mitra | |
| 787 | 0 | |n https://doaj.org/toc/2229-5178 | |
| 856 | 4 | 1 | |u https://doaj.org/article/d709b4530d064a37b4eb5ebe428f1a25 |z Connect to this object online. |