Antioxidative Self-Assembling Nanoparticles Attenuate the Development of Steatohepatitis and Inhibit Hepatocarcinogenesis in Mice

• Main Authors: Takahisa Watahiki (Author), Kosuke Okada (Author), Ikuru Miura (Author), Keii To (Author), Seiya Tanaka (Author), Eiji Warabi (Author), Naomi Kanno (Author), Kenji Yamagata (Author), Naohiro Gotoh (Author), Hideo Suzuki (Author), Shunichi Ariizumi (Author), Kiichiro Tsuchiya (Author), Yukio Nagasaki (Author), Junichi Shoda (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress (OS) contributes to nonalcoholic steatohepatitis (NASH) and hepatocarcinogenesis. We investigated whether antioxidative self-assembling nanoparticles (SMAPo^TN) could reduce the development of NASH and hepatocellular carcinoma (HCC) in <i>p62/Sqstm1</i...