Searching for a long-acting injectable formulation for the antiretroviral dolutegravir
The aim of this study was to engineer a DTG particle size able to provide plasma drug concentration maintenance above PA-IC-90 and, based on such drug prolonged- exposure, to evaluate the 30 days-acting injectable DTG feasibility for anti-HIV therapy. Liquid antisolvent precipitation technology was...
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University of Huddersfield Press,
2019-12-01T00:00:00Z.
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