Challenge and Development Strategy for Colon-Targeted Drug Delivery System
Colon-Targeted Drug Delivery System (CTDDS) is able to improve local therapeutic effects in the treatment of colon-specific diseases, such as Crohn's disease, Ulcerative Colitis (UC), and Irritable Bowel Syndrome (IBS). A colon can also be a suitable site for systemic delivery of drugs suscepti...
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| Main Authors: | , , , , |
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| Format: | Book |
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Universitas Indonesia,
2022-04-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Colon-Targeted Drug Delivery System (CTDDS) is able to improve local therapeutic effects in the treatment of colon-specific diseases, such as Crohn's disease, Ulcerative Colitis (UC), and Irritable Bowel Syndrome (IBS). A colon can also be a suitable site for systemic delivery of drugs susceptible to extreme gastric pH, such as peptides and protein therapeutics. The physiological conditions of the gastrointestinal tract and the physicochemical properties of drugs are being considered to develop strategies and approaches to overcome emerging challenges. This review will discuss factors, challenges, strategies, and approaches to developing a colon-targeted drug delivery system. |
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| Item Description: | https://doi.org/10.7454/psr.v9i1.1251 2407-2354 2477-0612 |