Physiologically Based Pharmacokinetic Modeling to Understand the Absorption of Risperidone Orodispersible Film

• Main Authors: Fang Chen (Author), Hongrui Liu (Author), Bing Wang (Author), Liuliu Yang (Author), Weimin Cai (Author), Zheng Jiao (Author), Zhou Yang (Author), Yusheng Chen (Author), Yingjun Quan (Author), Xiaoqiang Xiang (Author), Hao Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveThe aim of the present study was to investigate the absorption routes as well as the potential application of the oral transmucosal delivery of risperidone orodispersible film (ODF) using physiologically based pharmacokinetic modeling.MethodsThe pharmacokinetic study after intragastric (i.g...