Ribosomopathies: how a common root can cause a tree of pathologies

• 主要な著者: Nadia Danilova (著者), Hanna T. Gazda (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2015-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Defects in ribosome biogenesis are associated with a group of diseases called the ribosomopathies, of which Diamond-Blackfan anemia (DBA) is the most studied. Ribosomes are composed of ribosomal proteins (RPs) and ribosomal RNA (rRNA). RPs and multiple other factors are necessary for the processing...