Self-nanoemulsifying System Optimization for Higher Terconazole Solubilization and Non-Irritant Ocular Administration

• Hoofdauteurs: Carol Yousry (Auteur), Pakinam Mohsen Zikry (Auteur), Emad Basalious Basalious (Auteur), Omaima Naem El-Gazayerly (Auteur)
• Formaat: Boek
• Gepubliceerd in: Tabriz University of Medical Sciences, 2020-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Purpose: Eye drops' formulations of poorly water-soluble drugs, offer the advantage of crossing the lipophilic cornea, but their limited aqueous solubility may lead to low ocular bioavailability limiting their therapeutic uses. Terconazole (TZ) is an antifungal drug with low aqueous solubility,...