Profiles of Tumor-Infiltrating Lymphocytes in a Case of Trichilemmal Carcinoma with Spontaneous Regression
We describe the case of a 69-year-old Japanese patient with spontaneous regression of trichilemmal carcinoma. We investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Karger Publishers,
2012-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | We describe the case of a 69-year-old Japanese patient with spontaneous regression of trichilemmal carcinoma. We investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study describes some of the possible mechanisms of the self-regression of cutaneous malignant tumors and potential therapies for trichilemmal carcinoma by modifying the tumor microenvironment. |
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| Item Description: | 1662-6567 10.1159/000343881 |