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CYP3A5 and UGT1A9 Polymorphisms Influence Immunosuppressive Therapy in Pediatric Kidney Transplant Recipients

Background: Tacrolimus (TAC) and mycophenolic acid (MPA) are the main immunosuppressive drugs used in pediatric kidney transplantation. Single nucleotide polymorphisms (SNPs) in metabolizing enzymes and transporters might influence plasma levels of these drugs. Herein, we sought to determine the inf...

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Main Authors: Paola Krall (Author), Dominique Yañez (Author), Angélica Rojo (Author), Ángela Delucchi (Author), Miguel Córdova (Author), Jorge Morales (Author), Pía Boza (Author), Alonso de la Rivera (Author), Natalie Espinoza (Author), Natalia Armijo (Author), Luis E. Castañeda (Author), Mauricio J. Farfán (Author), Carolina Salas (Author)
Format: Book
Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
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