Dominant cross-reactive B cell response during secondary acute dengue virus infection in humans.

• Κύριοι συγγραφείς: Simona Zompi (Συγγραφέας), Magelda Montoya (Συγγραφέας), Marie O Pohl (Συγγραφέας), Angel Balmaseda (Συγγραφέας), Eva Harris (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The four serotypes of dengue virus (DENV) cause dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Severe disease has been associated with heterotypic secondary DENV infection, mediated by cross-reactive antibodies (Abs) and/or cross-reactive T cells. The role of cross-r...