Blockade of Leukotriene B4 Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer

• Κύριοι συγγραφείς: Aya Ihara (Συγγραφέας), Koichiro Wada (Συγγραφέας), Masato Yoneda (Συγγραφέας), Nobutaka Fujisawa (Συγγραφέας), Hirokazu Takahashi (Συγγραφέας), Atsushi Nakajima (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2007-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

We investigated whether leukotriene B4 (LTB4) and its signaling pathway play an important role in the progression of human colon cancer via a direct stimulation of cancer cell proliferation. Remarkable expression of LTB4 receptor 1 (BLT1) in human colon cancer tissues was detected by immunohistochem...