Bioanalytical method validation for therapeutic drug monitoring of olaparib in patients with ovarian cancer

• 主要な著者: Konrad Lewandowski (著者), Agnieszka Karbownik (著者), Andrzej Czyrski (著者), Hanna Urjasz (著者), Joanna Stanisławiak-Rudowicz (著者), Edmund Grześkowiak (著者), Edyta Szałek (著者)
• フォーマット: 図書
• 出版事項: Polskie Towarzystwo Farmaceutyczne, 2024-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Olaparib, an oral poly-ADP ribose polymerase (PARP) inhibitor, is a relatively new anticancer drug. It is essential to find TDM-guided dosage for better safety and tolerability of patients. However, first, it is important to develop a suitable analytical method to conduct reliable TDM. The aim of th...