Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• Prif Awduron: Mahmoud Kandeel (Awdur), Mizuki Yamamoto (Awdur), Byoung Kwon Park (Awdur), Abdulla Al-Taher (Awdur), Aya Watanabe (Awdur), Jin Gohda (Awdur), Yasushi Kawaguchi (Awdur), Kentaro Oh-hashi (Awdur), Hyung-Joo Kwon (Awdur), Jun-ichiro Inoue (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...