Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• Auteurs principaux: Mahmoud Kandeel (Auteur), Mizuki Yamamoto (Auteur), Byoung Kwon Park (Auteur), Abdulla Al-Taher (Auteur), Aya Watanabe (Auteur), Jin Gohda (Auteur), Yasushi Kawaguchi (Auteur), Kentaro Oh-hashi (Auteur), Hyung-Joo Kwon (Auteur), Jun-ichiro Inoue (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...