Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• Príomhchruthaitheoirí: Mahmoud Kandeel (Údar), Mizuki Yamamoto (Údar), Byoung Kwon Park (Údar), Abdulla Al-Taher (Údar), Aya Watanabe (Údar), Jin Gohda (Údar), Yasushi Kawaguchi (Údar), Kentaro Oh-hashi (Údar), Hyung-Joo Kwon (Údar), Jun-ichiro Inoue (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...