Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• मुख्य लेखकों: Mahmoud Kandeel (लेखक), Mizuki Yamamoto (लेखक), Byoung Kwon Park (लेखक), Abdulla Al-Taher (लेखक), Aya Watanabe (लेखक), Jin Gohda (लेखक), Yasushi Kawaguchi (लेखक), Kentaro Oh-hashi (लेखक), Hyung-Joo Kwon (लेखक), Jun-ichiro Inoue (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...