Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• Үндсэн зохиолчид: Mahmoud Kandeel (Зохиогч), Mizuki Yamamoto (Зохиогч), Byoung Kwon Park (Зохиогч), Abdulla Al-Taher (Зохиогч), Aya Watanabe (Зохиогч), Jin Gohda (Зохиогч), Yasushi Kawaguchi (Зохиогч), Kentaro Oh-hashi (Зохиогч), Hyung-Joo Kwon (Зохиогч), Jun-ichiro Inoue (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...