Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• Asıl Yazarlar: Mahmoud Kandeel (Yazar), Mizuki Yamamoto (Yazar), Byoung Kwon Park (Yazar), Abdulla Al-Taher (Yazar), Aya Watanabe (Yazar), Jin Gohda (Yazar), Yasushi Kawaguchi (Yazar), Kentaro Oh-hashi (Yazar), Hyung-Joo Kwon (Yazar), Jun-ichiro Inoue (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...