"From Nares to Wound: Exploring the mechanisms for Staphylococcal surgical site infections, implications for infection prevention"

Surgical site infections (SSIs) are important healthcare-associated infections, leading to increased morbidity and mortality, healthcare costs, and prolonged hospital stays. Staphylococcus aureus is an important and common microbial cause of SSI. Nasal carriage of S. aureus has been shown to be an i...

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Главные авторы: Darren P. R. Troeman (Автор), Jan A. J. W. Kluytmans (Автор)
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Опубликовано: Cambridge University Press, 2023-01-01T00:00:00Z.
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100 1 0 |a Darren P. R. Troeman  |e author 
700 1 0 |a Jan A. J. W. Kluytmans  |e author 
245 0 0 |a "From Nares to Wound: Exploring the mechanisms for Staphylococcal surgical site infections, implications for infection prevention" 
260 |b Cambridge University Press,   |c 2023-01-01T00:00:00Z. 
500 |a 10.1017/ash.2023.197 
500 |a 2732-494X 
520 |a Surgical site infections (SSIs) are important healthcare-associated infections, leading to increased morbidity and mortality, healthcare costs, and prolonged hospital stays. Staphylococcus aureus is an important and common microbial cause of SSI. Nasal carriage of S. aureus has been shown to be an important determinant for the development of SSI, and interventions aimed at eradicating preoperative nasal carriage are associated with a reduced risk of infection. Yet, it is not entirely clear how the nasally residing S. aureus causes SSI at distant body sites. In this commentary, we describe our view on how S. aureus can be transported from the nares to the incision site during surgery. In addition, we shed light on the implications of our view for infection prevention research. 
546 |a EN 
690 |a Infectious and parasitic diseases 
690 |a RC109-216 
690 |a Public aspects of medicine 
690 |a RA1-1270 
655 7 |a article  |2 local 
786 0 |n Antimicrobial Stewardship & Healthcare Epidemiology, Vol 3 (2023) 
787 0 |n https://www.cambridge.org/core/product/identifier/S2732494X23001973/type/journal_article 
787 0 |n https://doaj.org/toc/2732-494X 
856 4 1 |u https://doaj.org/article/d92d1427d2574b8cb153b70cea347002  |z Connect to this object online.