Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth

ObjectiveWe evaluated the effect on treatment using the new International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria for gestational diabetes mellitus (GDM) diagnosis.MethodsSingleton pregnant women whose plasma glucose levels were ≥140 mg/dL on the 50 g glucose challenge te...

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Main Authors: Kyoung-Hee Lee (Author), You-Jung Han (Author), Jin-Hoon Chung (Author), Moon-Young Kim (Author), Hyun-Mee Ryu (Author), Jin-Ha Kim (Author), Dong-Wook Kwak (Author), Sung-Hoon Kim (Author), Seongwoo Yang (Author), Minhyoung Kim (Author)
Format: Book
Published: Korean Society of Obstetrics and Gynecology, 2020-01-01T00:00:00Z.
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001 doaj_d93898fc84a54a8b8dc620f65a6d156f
042 |a dc 
100 1 0 |a Kyoung-Hee Lee  |e author 
700 1 0 |a You-Jung Han  |e author 
700 1 0 |a Jin-Hoon Chung  |e author 
700 1 0 |a Moon-Young Kim  |e author 
700 1 0 |a Hyun-Mee Ryu  |e author 
700 1 0 |a Jin-Ha Kim  |e author 
700 1 0 |a Dong-Wook Kwak  |e author 
700 1 0 |a Sung-Hoon Kim  |e author 
700 1 0 |a Seongwoo Yang  |e author 
700 1 0 |a Minhyoung Kim  |e author 
245 0 0 |a Treatment of gestational diabetes diagnosed by the IADPSG criteria decreases excessive fetal growth 
260 |b Korean Society of Obstetrics and Gynecology,   |c 2020-01-01T00:00:00Z. 
500 |a 2287-8572 
500 |a 2287-8580 
500 |a 10.5468/ogs.2020.63.1.19 
520 |a ObjectiveWe evaluated the effect on treatment using the new International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria for gestational diabetes mellitus (GDM) diagnosis.MethodsSingleton pregnant women whose plasma glucose levels were ≥140 mg/dL on the 50 g glucose challenge test (GCT) underwent 75 g oral glucose tolerance for GDM diagnosis. During the first half of the study period, GDM was diagnosed using 2 abnormal values by Carpenter-Coustan (C-C) criteria. In the second half of the study period, 1 or more abnormal values by IADPSG criteria were used for GDM diagnosis. Pregnant women were classified into 5 groups: normal 50 g GCT, positive 50 g GCT but non-GDM, GDM by IADPSG criteria and non-treated, GDM by IADPSG criteria and treated, GDM by C-C criteria and treated. The odds ratios (ORs) for large for gestational age (LGA) and macrosomia were analyzed.ResultsOf the 2,678 patients, the frequency of GDM diagnosed by C-C and IADPSG criteria was 2.6% and 7.5%. ORs (95% confidence intervals [CIs]) for LGA and macrosomia in the group with GDM by IADPSG criteria and non-treated were 2.81 (95% CI, 1.47-5.38) and 2.84 (95% CI, 1.08-7.47). The risk of LGA and macrosomia did not increase in the group with GDM by IADPSG criteria and treated.ConclusionThe risk of LGA and macrosomia for mild GDM diagnosed solely by IADPSG criteria depends on whether they are treated or not. Treatment of GDM based on IADPSG criteria reduces the risk of excessive fetal growth.Trial RegistrationClinical Research Information Service Identifier: KCT0000776 
546 |a EN 
546 |a KO 
690 |a gestational diabetes 
690 |a criteria 
690 |a treatment 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Obstetrics & Gynecology Science, Vol 63, Iss 1, Pp 19-26 (2020) 
787 0 |n http://ogscience.org/upload/pdf/ogs-63-19.pdf 
787 0 |n https://doaj.org/toc/2287-8572 
787 0 |n https://doaj.org/toc/2287-8580 
856 4 1 |u https://doaj.org/article/d93898fc84a54a8b8dc620f65a6d156f  |z Connect to this object online.