Network analysis and experimental pharmacology study explore the protective effects of Isoliquiritigenin on 5-fluorouracil-Induced intestinal mucositis

• Main Authors: Yi-fan Liao (Author), Feng-lin Luo (Author), Shan-shan Tang (Author), Jing-wei Huang (Author), Ying Yang (Author), Shuang Wang (Author), Tang-yu Jiang (Author), Qiong Man (Author), Sha Liu (Author), Yi-ying Wu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

5-fluorouracil (5-FU) is one of the most widely used chemotherapy drugs for malignant tumors. However, intestinal mucositis caused by 5-FU is a severe dose-limiting toxic effect and even leads to treatment interruption. Isoliquiritigenin (ISL) is one of the main active compounds of licorice, which i...