β-Cell Autophagy Pathway and Endoplasmic Reticulum Stress Regulating-Role of Liposomal Curcumin in Experimental Diabetes Mellitus: A Molecular and Morphometric Study

• Main Authors: Safaa I. Khater (Author), Mohamed F. Dowidar (Author), Aya E. Abdel-Aziz (Author), Tarek Khamis (Author), Naief Dahran (Author), Leena S. Alqahtani (Author), Mohamed M. M. Metwally (Author), Al-Sa (Author), Mohammed Alsieni (Author), Manal E. Alosaimi (Author), Maram H. Abduljabbar (Author), Amany Abdel-Rahman Mohamed (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Autophagy can confer protection to pancreatic β-cells from the harmful effects of metabolic stress by delaying apoptosis. Curcumin (CUR) alleviates oxidative and endoplasmic reticulum (ER) stress, activates autophagy, reduces inflammation, and decreases β-cell damage in type I diabetes....