Carbohydrates Used in Polymeric Systems for Drug Delivery: From Structures to Applications

Carbohydrates, one of the most important compounds in living organisms, perform numerous roles, including those associated with the extracellular matrix, energy-related compounds, and information. Of these, polymeric carbohydrates are a class of substance with a long history in drug delivery that ha...

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Main Authors: Xiangjie Di (Author), Xiao Liang (Author), Chao Shen (Author), Yuwen Pei (Author), Bin Wu (Author), Zhiyao He (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Xiangjie Di  |e author 
700 1 0 |a Xiao Liang  |e author 
700 1 0 |a Chao Shen  |e author 
700 1 0 |a Yuwen Pei  |e author 
700 1 0 |a Bin Wu  |e author 
700 1 0 |a Zhiyao He  |e author 
245 0 0 |a Carbohydrates Used in Polymeric Systems for Drug Delivery: From Structures to Applications 
260 |b MDPI AG,   |c 2022-03-01T00:00:00Z. 
500 |a 10.3390/pharmaceutics14040739 
500 |a 1999-4923 
520 |a Carbohydrates, one of the most important compounds in living organisms, perform numerous roles, including those associated with the extracellular matrix, energy-related compounds, and information. Of these, polymeric carbohydrates are a class of substance with a long history in drug delivery that have attracted more attention in recent years. Because polymeric carbohydrates have the advantages of nontoxicity, biocompatibility, and biodegradability, they can be used in drug targeting, sustained drug release, immune antigens and adjuvants. In this review, various carbohydrate-based or carbohydrate-modified drug delivery systems and their applications in disease therapy have been surveyed. Specifically, this review focuses on the fundamental understanding of carbohydrate-based drug delivery systems, strategies for application, and the evaluation of biological activity. Future perspectives, including opportunities and challenges in this field, are also discussed. 
546 |a EN 
690 |a carbohydrate-based polymer 
690 |a drug delivery 
690 |a hydrogel 
690 |a nanoparticle 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Pharmaceutics, Vol 14, Iss 4, p 739 (2022) 
787 0 |n https://www.mdpi.com/1999-4923/14/4/739 
787 0 |n https://doaj.org/toc/1999-4923 
856 4 1 |u https://doaj.org/article/d99b80fcce6d41a48fe76e908d4a5e13  |z Connect to this object online.