Investigation of simplified physiologically‐based pharmacokinetic models in rat and human

• Главные авторы: Estelle Yau (Автор), Andrés Olivares‐Morales (Автор), Kayode Ogungbenro (Автор), Leon Aarons (Автор), Michael Gertz (Автор)
• Формат: ‌
• Опубликовано: Wiley, 2023-03-01T00:00:00Z.
• Предметы: article
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Abstract Whole‐body physiologically‐based pharmacokinetic (PBPK) models have many applications in drug research and development. It is often necessary to inform these models with animal or clinical data, updating model parameters, and making the model more predictive for future applications. This pr...