Thermosensitive PLGA-PEG-PLGA Hydrogel as Depot Matrix for Allergen-Specific Immunotherapy

• Main Authors: Sonja Heine (Author), Antonio Aguilar-Pimentel (Author), Dennis Russkamp (Author), Francesca Alessandrini (Author), Valerie Gailus-Durner (Author), Helmut Fuchs (Author), Markus Ollert (Author), Reinhard Bredehorst (Author), Caspar Ohnmacht (Author), Ulrich M. Zissler (Author), Martin Hrabě de Angelis (Author), Carsten B. Schmidt-Weber (Author), Simon Blank (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Allergen-specific immunotherapy (AIT) is the only currently available curative treatment option for allergic diseases. AIT often includes depot-forming and immunostimulatory adjuvants, to prolong allergen presentation and to improve therapeutic efficacy. The use of aluminium salts in AIT, which are...