Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation

• Main Authors: Die Hu (Author), Shintaro Fumoto (Author), Hirotaka Miyamoto (Author), Masakazu Tanaka (Author), Koyo Nishida (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2022-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The generation of reactive oxygen species (ROS) can affect cationic liposome-mediated transfection. In this study, we focused on a specific class of antioxidants, flavonoids, to investigate the transfection efficiency using cationic liposome/plasmid DNA complexes (lipoplexes) in 2D and 3D cultures o...