Scutellarin inhibits caspase-11 activation and pyroptosis in macrophages via regulating PKA signaling
Inflammatory caspase-11 senses and is activated by intracellular lipopolysaccharide (LPS) leading to pyroptosis that has critical role in defensing against bacterial infection, whereas its excess activation under pathogenic circumstances may cause various inflammatory diseases. However, there are fe...
Saved in:
Main Authors: | Jiezhou Ye (Author), Bo Zeng (Author), Meiyan Zhong (Author), Hongchun Li (Author), Lihui Xu (Author), Junxiang Shu (Author), Yaofeng Wang (Author), Fan Yang (Author), Chunsu Zhong (Author), Xunjia Ye (Author), Xianhui He (Author), Dongyun Ouyang (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2021-01-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Quercetin inhibits caspase-1-dependent macrophage pyroptosis in experimental folic acid nephropathy
by: Xianli Gao, et al.
Published: (2024) -
Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis
by: Yi Liu, et al.
Published: (2018) -
Bitongqing Attenuates CIA Rats by Suppressing Macrophage Pyroptosis and Modulating the NLRP3/Caspase-1/GSDMD Pathway
by: Wu Y, et al.
Published: (2024) -
Downregulation of HMGB1 carried by macrophage-derived extracellular vesicles delays atherosclerotic plaque formation through Caspase-11-dependent macrophage pyroptosis
by: Weijie Liang, et al.
Published: (2024) -
Inflammatory Caspases Drive Pyroptosis in Acute Lung Injury
by: Bohao Liu, et al.
Published: (2021)