Genome evolution of SARS-CoV-2 and its virological characteristics
Abstract Coronavirus disease of 2019 (COVID-19), which originated in China in 2019, shows mild cold and pneumonia symptoms that can occasionally worsen and result in deaths. SARS-CoV-2 was reported to be the causative agent of the disease and was identified as being similar to SARS-CoV, a causative...
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BMC,
2020-08-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_da4b171a6f994517a904bda5182f2c6a | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a So Nakagawa |e author |
| 700 | 1 | 0 | |a Takayuki Miyazawa |e author |
| 245 | 0 | 0 | |a Genome evolution of SARS-CoV-2 and its virological characteristics |
| 260 | |b BMC, |c 2020-08-01T00:00:00Z. | ||
| 500 | |a 10.1186/s41232-020-00126-7 | ||
| 500 | |a 1880-8190 | ||
| 520 | |a Abstract Coronavirus disease of 2019 (COVID-19), which originated in China in 2019, shows mild cold and pneumonia symptoms that can occasionally worsen and result in deaths. SARS-CoV-2 was reported to be the causative agent of the disease and was identified as being similar to SARS-CoV, a causative agent of SARS in 2003. In this review, we described the phylogeny of SARS-CoV-2, covering various related studies, in particular, focusing on viruses obtained from horseshoe bats and pangolins that belong to Sarbecovirus, a subgenus of Betacoronavirus. We also describe the virological characteristics of SARS-CoV-2 and compare them with other coronaviruses. More than 30,000 genome sequences of SARS-CoV-2 are available in the GISAID database as of May 28, 2020. Using the genome sequence data of closely related viruses, the genomic characteristics and evolution of SARS-CoV-2 were extensively studied. However, given the global prevalence of COVID-19 and the large number of associated deaths, further computational and experimental virological analyses are required to fully characterize SARS-CoV-2. | ||
| 546 | |a EN | ||
| 690 | |a COVID-19 | ||
| 690 | |a Coronavirus | ||
| 690 | |a Comparative genomics | ||
| 690 | |a SARS-CoV-2 | ||
| 690 | |a Viral evolution | ||
| 690 | |a Pathology | ||
| 690 | |a RB1-214 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Inflammation and Regeneration, Vol 40, Iss 1, Pp 1-7 (2020) | |
| 787 | 0 | |n http://link.springer.com/article/10.1186/s41232-020-00126-7 | |
| 787 | 0 | |n https://doaj.org/toc/1880-8190 | |
| 856 | 4 | 1 | |u https://doaj.org/article/da4b171a6f994517a904bda5182f2c6a |z Connect to this object online. |